Publications
Journal Articles
Years: 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005
2022

- Wang H, Perera L, Jork N, Zong G, Riley A, Potter B, Jessen HJ, Shears S
A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop
2022 Nature Commun - Benjamin B, Garg A, Jork N, Jessen HJ, Schwer B, Shuman S
Activities and structure-function analysis of fission yeast inositol pyrophosphate (IPP) kinase-pyrophosphatase Asp1 and its impact on regulation of pho1 gene expression
2022 mBio, page: accepted - Gaugler P, Schneider R, Liu G, Qiu D, Weber J, Schmid J, Jork N, Häner M, Ritter K, Fernández Rebollo N, Giehl R, Trung M, Yadav R, Fiedler D, Gaugler V, Jessen HJ, Schaaf G, Laha D
Arabidopsis PFA-DSP-type phosphohydrolases target specific inositol pyrophosphate messengers
2022 Biochemistry, page: accepted - Shepard S, Jessen HJ*, Cummins CC*
Beyond Triphosphates: Reagents and Methods for Chemical Oligophosphorylation
2022 J. Am. Chem. Soc. - Haas TM, Laventie B-J, Lagies S, Harter C, Prucker I, Ritz D, Saleem-Batcha R, Qiu D, Hüttel W, Andexer J, Kammerer B, Jenal U, Jessen HJ
Photoaffinity Capture Compounds to Profile the Magic Spot Nucleotide Interactomes
2022 Angew. Chem. Int. Ed. - Haas TM, Mundinger S, Qiu D, Jork N, Ritter K, Dürr-Mayer T, Ripp A, Saiardi A, Schaaf G, Jessen HJ
Stable isotope phosphate labelling of diverse metabolites is enabled by a family of 18O-phosphoramidites
2022 Angew. Chem. Int. Ed., volume: 21, page: e202112457 - Haas TM, Wiesler S, Dürr-Mayer T, Ripp A, Fouka P, Qiu D, Jessen HJ
The Aryne Phosphate Reaction
2022 Angew. Chem. Int. Ed., volume: 61, page: e202113231
2021

- Jacoby C, Goerke M, Bezold D, Jessen HJ, Boll M
A fully reversible 25-hydroxy steroid kinase involved in oxygen-independent cholesterol side-chain oxidation
2021 J Biol Chem - Qiu D, Eisenbeis VB, Saiardi A, Jessen HJ
Absolute Quantitation of Inositol Pyrophosphates by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry
2021 J Vis Exp - Riemer E, Qiu D, Laha D, Harmel R, Gaugler P, Gaugler V, Frei M, Hajirezaei MR, Laha NP, Krusenbaum L, Schneider R, Saiardi A, Fiedler D, Jessen HJ, Schaaf G, Giehl RF
ITPK1 is an InsP6/ADP phosphotransferase that controls systemic phosphate signaling in Arabidopsis
2021 Molecular Plant - Wang D, Li Y, Cope HA, Li X, He P, C Liu, Li G, Rahman SM, Tooker NB, Bott CB, Onnis-Hayden A, Singh J, Elfick A, Marquez R, Jessen HJ, Oehmen A, Gu AZ
Intracellular Polyphosphate Length Characterization in Polyphosphate Accumulating Microorganisms (PAOs): Implications in PAO Phenotypic Diversity and Enhanced Biological Phosphorus Removal Performance
2021 Water Research - Jessen HJ, Dürr-Mayer T, Haas TM, Ripp A, Cummins CC
Lost in Condensation: Poly-, Cyclo-, and Ultraphosphates
2021 Acc. Chem. Res. - Zong G, Jork N, Hostachy S, Fiedler D, Jessen HJ, Shears SB, Wang H
New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.
2021 Faseb J, volume: 35, page: e21275 - Samper-Martín B, Sarrias A, Lázaro B, Pérez-Montero M, Rodríguez-Rodríguez R, Ribeiro MPC, Bañón A, Wolfgeher D, Jessen HJ, Alsina B, Clotet J, Kron SJ, Saiardi A, Jiménez J, Bru S
Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response
2021 Cell Rep. - Wang X, Bittner T, Milanov M, Kaul L, Mundinger S, Koch HG, Jessen-Trefzer C, Jessen HJ
Pyridinium modified anthracenes and their endoperoxides provide a tunable scaffold with activity against gram-positive and gram-negative bacteria
2021 ACS Infectious Diseases, volume: 7, pages: 2073 - 2080 - Vranas M, Wohlwend D, Qiu D, Gerhardt S, Trncik C, Pervaiz M, Ritter K, Steimle S, Randazzo A, Einsle O, Günther S, Jessen HJ, Kotlyar A, Friedrich T
Structural Basis for Inhibition of ROS-Producing Respiratory Complex I by NADH-OH
2021 Angew. Chem. Int. Ed. - Dürr-Mayer T, Qiu D, Eisenbeis VB, Steck N, Häner M, Hofer A, Mayer A, Siegel JS, Baldridge KK, Jessen HJ
The Chemistry of Branched Condensed Phosphates
2021 Nature Communications, volume: 12, page: 5368 - BS Mantilla, LD Do Amaral, HJ Jessen, R Docampo
The Inositol Pyrophosphate Biosynthetic Pathway of Trypanosoma cruzi
2021 ACS Chem Biol, volume: 16, pages: 283 - 292 - Desfougères Y, Portela-Torres P, Qiu D, Livermore TM, Harmel RK, Borghi F, Jessen HJ, Fiedler D, Saiardi A
The inositol pyrophosphate metabolism of Dictyostelium discoideum does not regulate inorganic polyphosphate (polyP) synthesis
2021 Adv. Biol. Regul. - Moumbock, A, Li, J, Tran, H, Hinkelmann, R, Lamy, E, Jessen, HJ, Günther, S
ePharmaLib: A Versatile Library of e-Pharmacophores to Address Small-Molecule (Poly-)Pharmacology
2021 J. Chem. Inf. Model., volume: 61, pages: 3659 - 3666
2020

- Jacoby C, Ferlaino S, Bezold D, Jessen HJ, Müller M, Boll M
ATP-dependent hydroxylation of an unactivated primary carbon with water
2020 Nat Commun, volume: 11, page: 3906 - Qiu D, Wilson MS, Eisenbeis VB, Harmel RC, Riemer E, Haas TM, Wittwer C, Jork N, Gu C, Shears SB, Schaaf G, Kammerer B, Fiedler D, Saiardi A, Jessen HJ
Analysis of Inositol Phosphate Metabolism by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry
2020 Nat Commun, volume: 11, page: 6035 - Li X, Gu C, Hostachy S, Sahu S, Wittwer C, Jessen HJ, Fiedler D, Wang H, Shears SB
Control of XPR1-dependent cellular phosphate efflux by InsP8 is an exemplar for functionally-exclusive inositol pyrophosphate signaling
2020 P Natl Acad Sci Usa, volume: 117, pages: 3568 - 3574 - Bezold D, Dürr T, Singh J, Jessen HJ
Cyclotriphosphate: A Brief History, Recent Developments, and Perspectives in Synthesis
2020 Chem-eur J, volume: 26, pages: 2298 - 2308 - Azevedo C, Desfougeres Y, Jiramongkol Y, Partington H, Trakansuebkul S, Singh J, Steck N, Jessen HJ, Saiardi A
Development of a yeast model to study the contribution of vacuolar polyphosphate metabolism to lysine polyphosphorylation.
2020 J Biol Chem, volume: 295, pages: 1439 - 1451 - Haas T, Qiu D, Häner M, Angebauer L, Ripp A, Singh J, Koch HG, Jessen-Trefzer C, Jessen HJ
Four phosphates at one blow: access to pentaphosphorylated magic spot nucleotides and their analysis by capillary electrophoresis
2020 J Org Chem, volume: 85, pages: 14496 - 14506 - Gutacker F, Schmidt-Bohli YI, Strobel T, Qiu D, Jessen HJ, Paululat T, Bechthold A
Identification and characterization of a novel N- and O-glycosyltransferase from Saccharopolyspora erythraea
2020 Molecules, volume: 25, page: 3400 - Sahu S, Wang Z, Jiao X, Gu C, Jork N, Wittwer C, Li X, Hostachy S, Fiedler D, Wang H, Jessen HJ, Kiledjian M, Shears SB
InsP7 is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics.
2020 P Natl Acad Sci Usa, volume: 117, pages: 19245 - 19253 - Deng J, Bezold D, Jessen HJ, Walther A
Multiple Light Control Mechanisms in ATP‐fueled Non‐Equilibrium DNA Systems
2020 Angew Chem Int Edit, volume: 59, pages: 12084 - 12092 - Hauke S, Bittner T, Jessen HJ*, Schultz C*
Photo-releasable derivatives of inositol pyrophosphates
2020 Method Enzymol, volume: 641, pages: 53 - 73 - Bittner T, Wittwer C, Hauke S, Wohlwend D, Mundinger S, Dutta A, Bezold D, Dürr T, Friedrich T, Schultz C, Jessen HJ
Photolysis of caged inositol-pyrophosphate InsP8 directly modulates intracellular Ca2+ oscillations and controls C2AB domain localization
2020 J Am Chem Soc, volume: 142, pages: 10606 - 10611 - Ripp A, Singh J, Jessen HJ
Rapid Synthesis of Nucleoside Triphosphates and Analogues
2020 Current Protocols in Nucleic Acid Chemistry, volume: 81, page: e108 - Wang Z, Jork N, Bittner T, Wang H, Jessen HJ, Shears SB
Rapid stimulation of cellular Pi uptake by the inositol pyrophosphate InsP8 induced by its photothermal release from lipid nanocarriers using a near infra-red light-emitting diode
2020 Chem Sci, volume: 11, pages: 10625 - 10278 - Chin AC, Gao Z, Riley AM, Furkert D, Wittwer C, Dutta AK, Rojas T, Semenza ER, Felder RA, Pluznick JL, Jessen HJ, Fiedler D, Potter BVL, Snyder SH, Fu C
The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α
2020 Sci Adv, volume: 6, page: eabb8542 - Ma J, Ripp A, Wassy D, Dürr T, Qiu D, Häner M, Haas TM, Popp C, Bezold D, Richert S, Esser B, Jessen HJ
Thiocoumarin Caged Nucleotides: Synthetic Access and Their Photophysical Properties
2020 Molecules, volume: 25, page: 5325
2019

- Singh J, Steck N, De D, Hofer A, Ripp A, Captain I, Keller M, Wender PA, Bhandari R, Jessen HJ
A Phosphoramidite Analog of Cyclotriphosphate Enables Iterative Polyphosphorylations
2019 Angew Chem Int Edit, volume: 58, pages: 3928 - 3933 - Laha D, Parvin N, Hofer A, Giehl R, Fernandez-Rebollo N, von Wiren N, Saiardi A, Jessen HJ, Schaaf G
Arabidopsis ITPK1 and ITPK2 have an Evolutionary Conserved Phytic Acid Kinase Activity
2019 Acs Chem Biol, volume: 14, pages: 2127 - 2123 - Wang H, Jessen HJ, Shears SB
Comprehensive snapshots of an unusual reaction cycle for an atypical protein tyrosine phosphatase (PTP)
2019 Faseb J, volume: 33 - An Y, Jessen HJ, Wang H, Shears S, Kireev D
Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine
2019 Structure, volume: 27, pages: 1022 - 1028 - Dong J, Ma G, Sui L, Wei M, Satheesh V, Zhang R, Ge S, Li J, Zhang TE, Wittwer C, Jessen HJ, Zhang H, An GY, Chao DY, Liu D, Lei M
Inositol Pyrophosphate InsP8 Acts as an Intracellular Phosphate Signal in Arabidopsis
2019 Mol Plant, volume: 12, pages: 1463 - 1473 - Kim W, Kim E, Min H, Kim MG, Eisenbeis VB, Dutta AK, Pavlovic I, Jessen HJ, Kim S, Seong RH
Inositol polyphosphates promote T cell-independent humoral immunity via the regulation of Bruton's tyrosine kinase
2019 P Natl Acad Sci Usa, volume: 116, pages: 12952 - 12957 - Duss M, Vallooran J, Salvati Manni L, Handschin S, Mezzenga R, Jessen HJ, Landau E
Lipidic Mesophase-embedded Palladium Nanoparticles: Synthesis and Tunable Catalysts in Suzuki-Miyaura Cross Coupling Reactions
2019 Langmuir, volume: 35, pages: 120 - 127 - Haas TM, Ebensperger P, Eisenbeis VB, Nopper C, Dürr T, Jork N, Steck N, Jessen-Trefzer C, Jessen HJ
Magic Spot Nucleotides: Tunable Target-specific Chemoenzymatic Synthesis
2019 Chem Commun, volume: 55, pages: 5339 - 5342 - Hauke S, Dutta AK, Eisenbeis V, Bezold D, Bittner T, Wittwer C, Thakor D, Pavlovic I, Schultz C*, Jessen HJ*
Photolysis of cell-permeant caged inositol pyrophosphates controls oscillations of cytosolic calcium in a β-cell line
2019 Chem Sci, volume: 10, pages: 2687 - 2692 - Mordhorst S, Singh J, Mohr MKF, Hinkelmann R, Keppler M, Jessen HJ*, Andexer JN*
Several Polyphosphate Kinase 2 Enzymes Catalyse the Production of Adenosine 5′‐Polyphosphates
2019 Chembiochem, volume: 20, pages: 1019 - 1022 - Singh J, Ripp A, Haas TM, Qiu D, Keller M, Wender PA, Siegel JS, Baldridge KK, Jessen HJ
Synthesis of modified nucleoside oligophosphates simplified: Fast, pure, and protecting group free
2019 J Am Chem Soc, volume: 141, pages: 15013 - 15017 - Wilson MS, Jessen HJ, Saiardi A
The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export
2019 J Biol Chem, volume: 294, pages: 11597 - 11608 - Dutta AK, Choudhary E, Wang X, Zahorszka M, Forbak M, Lohner P, Jessen HJ, Agarwal N, Kordulakova J, Jessen-Trefzer C
Trehalose-conjugation enhances toxicity of photosensitizers against mycobacteria
2019 Acs Central Sci, volume: 5, pages: 644 - 650 - Zhu J, Lau K, Puschmann R, Harmel RK, Zhang Y, Pries V, Gaugler P, Broger L, Dutta AK, Jessen HJ, Schaaf G, Fernie AR, Hothorn LA, Fiedler D, Hothorn M
Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis
2019 Elife, volume: 8
2018

- Potapenko E, Cordeiro C, Huang G, Storey M, Wittwer C, Dutta A, Jessen HJ, Starai VJ, Docampo R
5-Diphospho-Inositol Pentakisphosphate (5-IP7) Regulates Phosphate Release from Acidocalcisomes of Trypanosoma brucei and Vacuoles of Saccharomyces cerevisiae
2018 J Biol Chem, volume: 293, pages: 19101 - 19112 - Fernandes-Cunha GM, McKinlay C, Vargas J, Jessen HJ, Waymouth R, Wender PA
Delivery of Inorganic Polyphosphate into Cells using Amphipathic Oligocarbonate Transporters
2018 Acs Central Sci, volume: 4, pages: 1394 - 1402 - Ito M, Fujii N, Wittwer C, Sasaki A, Tanaka M, Bittner T, Jessen HJ, Saiardi A, Takizawa S
Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the quantitative analysis of mammalian-derived inositol poly/pyrophosphates
2018 J Chromatogr A, volume: 1573, pages: 87 - 97 - Nair VS, Gu C, Janoshazi AK, Jessen HJ, Wang H, Shears SB
Inositol Pyrophosphate Synthesis by Diphosphoinositol Pentakisphosphate Kinase-1 is Regulated by Phosphatidylinositol(4,5)bisphosphate.
2018 Bioscience Rep, volume: 38, page: BSR2017154 - Duss M, Salvati Manni L, Moser L, Handschin S, Mezzenga R, Jessen HJ, Landau E
Lipidic mesophases as novel nanoreactor scaffolds for organocatalysts: Heterogeneously catalyzed asymmetric aldol reactions in confined water
2018 Acs Appl Mater Inter, volume: 10, pages: 5114 - 5124 - Azevedo C, Singh J, Steck N, Hofer A, Ruiz F, Singh T, Jessen HJ*, Saiardi A*
Screening a protein array with synthetic biotinylated inorganic polyphosphate to define the human polyP-ome
2018 Acs Chem Biol, volume: 13, pages: 1958 - 1963 - Wang H, Gu C, Rolfes R, Jessen HJ, Shears SB
Structural and biochemical characterization of Siw14: a protein-tyrosine phosphatase fold that metabolizes inositol pyrophosphates.
2018 J Biol Chem, volume: 293, pages: 6905 - 6914 - Parnell A, Mordhorst S, Kemper F, Giurrandino M, Prince JR, Schwarzer NJ, Hofer A, Wohlwend D, Jessen HJ, Gerhardt S, Einsle O, Oyston PCF, Andexer JN, Roach PL
Substrate Recognition and Mechanism Revealed by Ligand-Bound Polyphosphate Kinase 2 Structures
2018 P Natl Acad Sci Usa, volume: 115, pages: 3350 - 3355 - Jessen HJ
The Hitchhiker’s Guide to Organophosphate Chemistry
2018 Synlett, volume: 29, pages: 699 - 713 - Puhl-Rubio AC, Stashko MA, Wang H, Hardy PB, Tyagi V, Li B, Wang X, Kireev D, Jessen HJ, Frye SV, Shears SB, Pearce KH
Use of Protein Kinase-Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors.
2018 SLAS Discovery, volume: 23, pages: 1 - 7
2017

- Blüher D, Laha D, Thieme S, Hofer A, Eschen-Lippold L, Masch A, Balcke G, Pavlovic I, Nagel O, Schonsky A, Hinkelmann R, Wörner J, Parvin N, Greiner R, Weber S, Tissier A, Schutkowski M, Lee J, Jessen HJ*, Schaaf G*, Bonas U*
A 1-phytase type III effector interferes with plant hormone signaling
2017 Nat Commun, volume: 8, page: 2159 - Chicca A, Berg R, Jessen HJ, Marck N, Schmid F, Burch P, Gertsch J, Gademann K
Biological Evaluation of Pyridone Alkaloids on the Endocannabinoid System
2017 Bioorgan Med Chem, volume: 25, pages: 6102 - 6114 - Jessen HJ
Editorial: Phosphate Labeling and Sensing in Chemical Biology
2017 Topics Curr Chem, volume: 375, issue: 51, pages: i - viii - Gerasimaite R, Pavlovic I, Capolicchio S, Hofer A, Schmidt A, Jessen HJ*, Mayer A*
Inositol pyrophosphate specificity of the SPX-dependent polyphosphate polymerase VTC
2017 Acs Chem Biol, volume: 12, pages: 648 - 653 - Gu C, Nguyen H-N, Ganini D, Chen Z, Jessen HJ, Gu Z, Wang H, Shears SB
Knockout of 5-InsP7 Kinase Activity Transforms the HCT116 Colon Cancer Cell line into a Hypermetabolic, Growth-Inhibited Phenotype.
2017 P Natl Acad Sci Usa, volume: 114, pages: 11968 - 11973 - Dutta A, Captain I, Jessen HJ
New Synthetic Methods for Phosphate Labeling
2017 Topics Curr Chem, volume: 375, issue: 51, pages: 105 - 152 - Gu C, Nguyen H-N, Hofer A, Jessen HJ, Dai X, Wang H, Shears SB
The Significance of the Bifunctional Kinase/Phosphatase Activities of PPIP5Ks for Coupling Inositol Pyrophosphate Cell-Signaling to Cellular Phosphate Homeostasis
2017 J Biol Chem, volume: 292, pages: 4544 - 4555
2016

- Pavlovic I, Thakor DT, Vargas JR, McKinlay CJ, Hauke S, Anstaett P, Camuna RC, Bigler L, Gasser G, Schultz C, Wender PA*, Jessen HJ*
Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo.
2016 Nat Commun, volume: 7, pages: 10622 - 10622 - Hofer A, Marques E, Kieliger N, Gatter SK, Jordi S, Ferrari E, Hofmann M, Fitzpatrick TB, Hottiger MO, Jessen HJ
Chemoselective Dimerization of Phosphates.
2016 Org Lett, volume: 18, issue: 13, pages: 3222 - 3225 - Wild R, Gerasimaite R, Jung JY, Truffault V, Pavlovic I, Schmidt A, Saiardi A, Jessen HJ, Poirier Y, Hothorn M, Mayer A
Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains.
2016 Science, volume: 352, issue: 6288, pages: 986 - 990 - Muller AC, Giambruno R, Weisser J, Majek P, Hofer A, Bigenzahn JW, Superti-Furga G, Jessen HJ*, Bennett KL*
Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry.
2016 Sci Rep-uk, volume: 6, pages: 28107 - 28107 - Gu C, Wilson MS, Jessen HJ, Saiardi A, Shears SB
Inositol Pyrophosphate Profiling of Two HCT116 Cell Lines Uncovers Variation in InsP8 Levels.
2016 Plos One, volume: 11, issue: 10, pages: e0165286 - e0165286 - Lee TS, Lee JY, Kyung JW, Yang Y, Park SJ, Lee S, Pavlovic I, Kong B, Jho YS, Jessen HJ, Kweon DH, Shin YK, Kim SH, Yoon TY, Kim S
Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis.
2016 P Natl Acad Sci Usa, volume: 113, issue: 29, pages: 8314 - 8319 - Pavlovic I, Thakor DT, Jessen HJ
Synthesis of 2-diphospho-myo-inositol 1,3,4,5,6-pentakisphosphate and a photocaged analogue.
2016 Org Biomol Chem, volume: 14, issue: 24, pages: 5559 - 5562 - Desfougeres Y, Gerasimaite R, Jessen HJ, Mayer A
Vtc5, a novel subunit of the vacuolar transporter chaperone complex, regulates polyphosphate synthesis and phosphate homeostasis in yeast
2016 J Biol Chem, volume: 291, pages: 22262 - 22275
2015

- Hofer A, Cremosnik GS, Muller AC, Giambruno R, Trefzer C, Superti-Furga G, Bennett KL, Jessen HJ
A Modular Synthesis of Modified Phosphoanhydrides.
2015 Chem-eur J, volume: 21, issue: 28, pages: 10116 - 10122 - Wang H, Nair VS, Holland AA, Capolicchio S, Jessen HJ, Johnson MK, Shears SB
Asp1 from Schizosaccharomyces pombe binds a [2Fe-2S](2+) cluster which inhibits inositol pyrophosphate 1-phosphatase activity.
2015 Biochemistry-us, volume: 54, issue: 42, pages: 6462 - 6474 - Duss M, Capolicchio S, Linden A, Ahmed N, Jessen HJ
Desymmetrization of myo-inositol derivatives by lanthanide catalyzed phosphitylation with C2-symmetric phosphites.
2015 Bioorgan Med Chem, volume: 23, issue: 12, pages: 2854 - 2861 - Pavlovic I, Thakor DT, Bigler L, Wilson MS, Laha D, Schaaf G, Saiardi A, Jessen HJ
Prometabolites of 5-Diphospho-myo-inositol Pentakisphosphate.
2015 Angew Chem Int Edit, volume: 54, issue: 33, pages: 9622 - 9626 - Meier C, Jessen HJ, Schulz T, Weinschenk L, Pertenbreiter ., Balzarini J
Rational Development of Nucleoside Diphosphate Prodrugs: DiPPro-Compounds
2015 Curr Med Chem, volume: 22, issue: 3933, supplement: 3950 - Laha D, Johnen P, Azevedo C, Dynowski M, Weiss M, Capolicchio S, Mao H, Iven T, Steenbergen M, Freyer M, Gaugler P, de Campos MK, Zheng N, Feussner I, Jessen HJ, Van Wees SC, Saiardi A, Schaaf G
VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP8 and Jasmonate-Dependent Defenses in Arabidopsis.
2015 Plant Cell, volume: 27, issue: 4, pages: 1082 - 1097
2014

- Schmid, F., Bernasconi, M., Jessen, H. J., Pfaltz, A., Gademann, K.
Catalytic Enantioselective Total Synthesis of (-)-Pyridovericin
2014 Synthesis-Stuttgart, volume: 46, issue: 7, pages: 864 - 870 - Jessen HJ, Capolicchio S, Pavlovic I, Thakor D
Diphosphoinositol Polyphosphates: Polar Stars in Cell Signaling
2014 Synlett, volume: 25, pages: 1494 - 1498 - Wu M, Chong LS, Capolicchio S, Jessen HJ, Resnick AC, Fiedler D
Elucidating diphosphoinositol polyphosphate function with nonhydrolyzable analogues.
2014 Angew Chem Int Edit, volume: 53, issue: 28, pages: 7192 - 7197 - Cremosnik GS, Hofer A, Jessen HJ
Iterative synthesis of nucleoside oligophosphates with phosphoramidites.
2014 Angew Chem Int Edit, volume: 53, issue: 1, pages: 286 - 289 - Jessen HJ, Ahmed N, Hofer A
Phosphate esters and anhydrides-recent strategies targeting nature's favoured modifications.
2014 Org Biomol Chem, volume: 12, issue: 22, pages: 3526 - 3530 - Capolicchio S, Wang H, Thakor DT, Shears SB, Jessen HJ
Synthesis of densely phosphorylated bis-1,5-diphospho-myo-inositol tetrakisphosphate and its enantiomer by bidirectional P-anhydride formation.
2014 Angew Chem Int Edit, volume: 53, issue: 36, pages: 9508 - 9511
2013

- Benz S, Notzli S, Siegel JS, Eberli D, Jessen HJ
Controlled oxygen release from pyridone endoperoxides promotes cell survival under anoxic conditions.
2013 J Med Chem, volume: 56, issue: 24, pages: 10171 - 10182 - Capolicchio S, Thakor DT, Linden A, Jessen HJ
Synthesis of unsymmetric diphospho-inositol polyphosphates.
2013 Angew Chem Int Edit, volume: 52, issue: 27, pages: 6912 - 6916 - Schoenebeck F, Jessen HJ
The 48 EUCHEMS Conference on Stereochemistry Burgenstock Conference 2013.
2013 Chimia, volume: 67, issue: 9, pages: 671 - 673 - Schmid, F., Jessen, H. J., Burch, P., Gademann, K.
Truncated militarinone fragments identified by total chemical synthesis induce neurite outgrowth
2013 Medchemcomm, volume: 4, issue: 1, pages: 135 - 139 - Liffert, R., Hoecker, J., Jana, C. K., Woods, T. M., Burch, P., Jessen, H. J., Neuburger, M., Gademann, K.
Withanolide A: synthesis and structural requirements for neurite outgrowth
2013 Chemical Science, volume: 4, issue: 7, pages: 2851 - 2857
2011

- Jessen HJ, Schumacher A, Shaw T, Pfaltz A, Gademann K
A unified approach for the stereoselective total synthesis of pyridone alkaloids and their neuritogenic activity.
2011 Angew Chem Int Edit, volume: 50, issue: 18, pages: 4222 - 4226 - Jessen HJ, Schumacher A, Schmid F, Pfaltz A, Gademann K
Catalytic enantioselective total synthesis of (+)-torrubiellone C.
2011 Org Lett, volume: 13, issue: 16, pages: 4368 - 4370 - Jana CK, Hoecker J, Woods TM, Jessen HJ, Neuburger M, Gademann K
Synthesis of withanolide A, biological evaluation of its neuritogenic properties, and studies on secretase inhibition.
2011 Angew Chem Int Edit, volume: 50, issue: 36, pages: 8407 - 8411
2010

- Jessen HJ, Gademann K
4-Hydroxy-2-pyridone alkaloids: structures and synthetic approaches.
2010 Nat Prod Rep, volume: 27, issue: 8, pages: 1168 - 1185 - Jessen HJ, Gademann K
Total synthesis of the marine alkaloid palau'amine.
2010 Angew Chem Int Edit, volume: 49, issue: 17, pages: 2972 - 2974
2009

- Jessen HJ, Barbaras D, Hamburger M, Gademann K
Total synthesis and neuritotrophic activity of farinosone C and derivatives.
2009 Org Lett, volume: 11, issue: 15, pages: 3446 - 3449
2008

- Jessen HJ, Schulz T, Balzarini J, Meier C
Bioreversible protection of nucleoside diphosphates.
2008 Angew Chem Int Edit, volume: 47, issue: 45, pages: 8719 - 8722 - Jessen HJ, Balzarini J, Meier C
Intracellular trapping of cycloSal-pronucleotides: modification of prodrugs with amino acid esters.
2008 J Med Chem, volume: 51, issue: 20, pages: 6592 - 6598 - Meier, C., Jessen, H. J., Balzarini, J.
Nucleoside diphosphate prodrugs
2008 Nucleic Acids Symp Ser (Oxf), issue: 52, pages: 83 - 4
2007

- Jessen, H. J., Tonn, V., Meier, C.
Intracellular trapping of cycloSal-pronucleotides by enzymatic cleavage
2007 Nucleos Nucleot Nucl, volume: 26, issue: 6-7, pages: 827 - 30
2006

- Meier C, Ducho C, Jessen HJ, Vukadinovic-Tenter D, Balzarini J
Second‐Generation cycloSal‐d4TMP Pronucleotides Bearing Esterase‐Cleavable Sites—The “Trapping” Concept
2006 Eur J Org Chem, volume: 1, pages: 197 - 206 - Jessen HJ, Fendrich W, Meier C
Synthesis and Properties of Fluorescent cycloSal Nucleotides Based on the Pyrimidine Nucleoside m5K and Its 2′, 3′‐Dideoxy Analog dm5K
2006 Eur J Org Chem, volume: 4, pages: 924 - 931
2005

- Meier, C., Ducho, C., Jessen, H. J., Balzarini, J.
Novel "lock-in" modified cycloSal nucleotides (II): Application of the AM- and the POM-group
2005 Antiviral Research, volume: 65, issue: 3, pages: A27 - A27
Credits: SILK Icons by http://www.famfamfam.com/lab/icons/silk/
Patents
H. J. Jessen, C. Meier; International Patent - Nr. PCT/DE2009/000550 |
H. J. Jessen, C. Meier; German Patent - Nr. DE 10 2008 020 633.4 |
Title and year of PhD thesis: “Studies on the intracellular release of nucleoside diphosphates”, 2008.